Moderate severity

Inflammatory Bowel Disease (IBD)

A chronic inflammation of the gut lining that leaves cats with long-running vomiting, diarrhoea and weight loss. It is one of the commonest causes of a cat that is repeatedly "sick" with no obvious infection.

⚠️ Common symptoms

Chronic or intermittent vomiting over weeks to monthsDiarrhoea, sometimes with mucus or bloodGradual weight loss despite a normal or increased appetiteReduced appetite in some catsA dull coat and general loss of conditionRumbling, gassy or uncomfortable abdomen

Inflammatory bowel disease is not a single illness so much as a description of what is happening: the lining of the stomach and intestines becomes chronically inflamed, infiltrated by the immune system's own cells, and stops working as it should. The result is a cat that is repeatedly unwell at one or both ends — vomiting, passing loose stools, and quietly losing weight over weeks and months — without the fever or sudden collapse of an acute infection.

Because the signs are vague and come and go, IBD is easily brushed off as a cat with a "delicate tummy" or a frequent hairball-bringer. But persistent vomiting and diarrhoea are never truly normal, and a cat that is slowly dropping weight while still eating is sending an important signal. The longer the inflammation runs unchecked, the more a cat's body condition and quality of life suffer.

Reaching a diagnosis takes some work, because many conditions — parasites, infections, an overactive thyroid, kidney or liver disease, food intolerance and intestinal cancer — produce the same picture. Vets typically work through blood tests, urine and faecal analysis, and ultrasound to narrow things down, and confirming IBD definitively requires a biopsy of the gut wall. That biopsy matters especially because IBD closely resembles, and can shade into, a slow-growing intestinal lymphoma; telling them apart changes both treatment and outlook.

The encouraging news is that most cats with IBD can be managed well once it is identified. A carefully chosen diet does much of the heavy lifting — many cats improve markedly on a hydrolysed or novel-protein food — and medication to dial down the over-active immune response controls the rest. It usually becomes a condition to manage for life rather than one that disappears, but with the right diet and treatment most affected cats return to a comfortable, stable life.

🔍 Causes

IBD is thought to result from an abnormal, ongoing immune response in the wall of the stomach and intestines, in which the gut's immune cells over-react to normal contents such as food proteins or the resident gut bacteria. The exact trigger is rarely pinpointed, but diet, the gut microbiome and genetic predisposition are all believed to play a part. Importantly, IBD can be difficult to tell apart from a low-grade intestinal lymphoma (cancer), and the two can even occur together — which is why thorough investigation matters.

🛡 Prevention

There is no guaranteed way to prevent IBD, but a consistent, good-quality diet, avoiding abrupt food changes, routine parasite control, and not ignoring early digestive signs all help. Because chronic vomiting and diarrhoea are easy to dismiss as a cat simply having a "sensitive stomach", catching and investigating persistent symptoms early gives the best chance of controlling the disease before a cat loses significant condition.

💊 Treatment

Treatment aims to calm the inflammation and identify dietary triggers, since IBD cannot usually be cured outright. A strict trial of a novel-protein or hydrolysed (hypoallergenic) diet is often the first and most important step. Where diet alone is not enough, anti-inflammatory medication — most commonly corticosteroids such as prednisolone — is used to control the immune over-reaction, sometimes alongside vitamin B12 injections, probiotics or other immune-modulating drugs. Treatment is usually long-term and tailored to the individual cat.

When to see a vet: See a vet if your cat is vomiting or has loose stools repeatedly over more than a week or two, is slowly losing weight, or has blood or mucus in its stools. Sudden severe vomiting, complete loss of appetite, or marked lethargy warrant prompt attention. Diagnosis usually needs blood tests, imaging and often a biopsy to confirm IBD and rule out other causes.

⚕️ Medical disclaimer

  • This information is educational only and is not a substitute for veterinary advice.
  • Symptoms overlap between conditions — only a vet can diagnose accurately.
  • Never withhold treatment or self-medicate based on information found online.
  • When in doubt, call your vet. Early intervention almost always leads to better outcomes.